![]() In cases with complex or unknown matrices, the standard addition method can be used. ![]() This is especially important for solid samples where there is a strong matrix influence. The most common approach for accounting for matrix effects is to build a calibration curve using standard samples with known analyte concentration and which try to approximate the matrix of the sample as much as possible. For example, the ionic strength of the solution can have an effect on the activity coefficients of the analytes. The matrix can have a considerable effect on the way the analysis is conducted and the quality of the results are obtained such effects are called matrix effects. ![]() In chemical analysis, matrix refers to the components of a sample other than the analyte of interest.
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